All-trans-10'-apo-beta-carotenal 13,14-cleaving dioxygenase

All-trans-10'-apo-beta-carotenal 13,14-cleaving dioxygenase (EC 1.13.11.70, CCD8 (gene), MAX4 (gene), NCED8 (gene)) is an enzyme with systematic name all-trans-10'-apo-beta-carotenal:O₂ oxidoreductase (13,14-cleaving).^[1] This enzyme catalyses the following chemical reaction

all-trans-10'-apo-beta-carotenal + O₂

\rightleftharpoons

13-apo-beta-carotenone + (2E,4E,6E)-4-methylocta-2,4,6-trienedial

The enzyme contains Fe²⁺.

References

↑ Schwartz, S.H.; Qin, X.; Loewen, M.C. (2004). "The biochemical characterization of two carotenoid cleavage enzymes from Arabidopsis indicates that a carotenoid-derived compound inhibits lateral branching". J. Biol. Chem. 279: 46940–46945. doi:10.1074/jbc.M409004200. PMID 15342640.

External links

All-trans-10'-apo-beta-carotenal 13,14-cleaving dioxygenase at the US National Library of Medicine Medical Subject Headings (MeSH)

Oxidoreductases: monooxygenases (EC 1.13)

1.13.11: two atoms of oxygen	lipoxygenase: Arachidonate 5-lipoxygenase Arachidonate 12-lipoxygenase/ALOX12 Arachidonate 8-lipoxygenase Arachidonate 15-lipoxygenase/ALOX15 Linoleate 11-lipoxygenase other dioxygenase: Catechol dioxygenase Homogentisate 1,2-dioxygenase Cysteine dioxygenase 4-Hydroxyphenylpyruvate dioxygenase Indoleamine 2,3-dioxygenase Chlorite dismutase

1.13.12: one atom of oxygen	Firefly luciferase

1.13.99: other	Inositol oxygenase

Enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list)

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