ATXN2L

ATXN2L
Identifiers
Aliases ATXN2L, A2D, A2LG, A2LP, A2RP, ataxin 2 like
External IDs MGI: 2446242 HomoloGene: 16513 GeneCards: ATXN2L
RNA expression pattern


More reference expression data
Orthologs
Species Human Mouse
Entrez

11273

233871

Ensembl

ENSG00000168488

ENSMUSG00000032637

UniProt

Q8WWM7

Q7TQH0

RefSeq (mRNA)

NM_183020

RefSeq (protein)

NP_898841.1

Location (UCSC) Chr 16: 28.82 – 28.84 Mb Chr 7: 126.49 – 126.5 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Ataxin-2-like protein is a protein that in humans is encoded by the ATXN2L gene.[3][4][5]

This gene encodes an ataxin type 2 related protein of unknown function. This protein is a member of the spinocerebellar ataxia (SCAs) family, which is associated with a complex group of neurodegenerative disorders. Several alternatively spliced transcripts encoding different isoforms have been found for this gene.[5]

Interactions

ATXN2L has been shown to interact with Myeloproliferative leukemia virus oncogene.[3]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. 1 2 Meunier C, Bordereaux D, Porteu F, Gisselbrecht S, Chretien S, Courtois G (Mar 2002). "Cloning and characterization of a family of proteins associated with Mpl". J Biol Chem. 277 (11): 9139–47. doi:10.1074/jbc.M105970200. PMID 11784712.
  4. Figueroa KP, Pulst SM (Feb 2004). "Identification and expression of the gene for human ataxin-2-related protein on chromosome 16". Exp Neurol. 184 (2): 669–78. doi:10.1016/S0014-4886(03)00287-5. PMID 14769358.
  5. 1 2 "Entrez Gene: ATXN2L ataxin 2-like".

Further reading


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