23S rRNA (guanine2445-N2)-methyltransferase
23S rRNA (guanine2445-N2)-methyltransferase | |||||||||
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Identifiers | |||||||||
EC number | 2.1.1.173 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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23S rRNA (guanine2445-N2)-methyltransferase (EC 2.1.1.173, ycbY (gene), rlmL (gene)) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (guanine2445-N2)-methyltransferase.[1] This enzyme catalyses the following chemical reaction
- S-adenosyl-L-methionine + guanine2445 in 23S rRNA S-adenosyl-L-homocysteine + N2-methylguanine2445 in 23S rRNA
The enzyme methylates 23S rRNA in vitro.
References
- ↑ Lesnyak, D.V.; Sergiev, P.V.; Bogdanov, A.A.; Dontsova, O.A. (2006). "Identification of Escherichia coli m2G methyltransferases: I. the ycbY gene encodes a methyltransferase specific for G2445 of the 23 S rRNA". J. Mol. Biol. 364: 20–25. doi:10.1016/j.jmb.2006.09.009. PMID 17010378.
External links
- 23S rRNA (guanine2445-N2)-methyltransferase at the US National Library of Medicine Medical Subject Headings (MeSH)
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