23S rRNA (guanine2445-N2)-methyltransferase

23S rRNA (guanine2445-N2)-methyltransferase
Identifiers
EC number 2.1.1.173
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

23S rRNA (guanine2445-N2)-methyltransferase (EC 2.1.1.173, ycbY (gene), rlmL (gene)) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (guanine2445-N2)-methyltransferase.[1] This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + guanine2445 in 23S rRNA S-adenosyl-L-homocysteine + N2-methylguanine2445 in 23S rRNA

The enzyme methylates 23S rRNA in vitro.

References

  1. Lesnyak, D.V.; Sergiev, P.V.; Bogdanov, A.A.; Dontsova, O.A. (2006). "Identification of Escherichia coli m2G methyltransferases: I. the ycbY gene encodes a methyltransferase specific for G2445 of the 23 S rRNA". J. Mol. Biol. 364: 20–25. doi:10.1016/j.jmb.2006.09.009. PMID 17010378.

External links

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