2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase

2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase
Identifiers
EC number 5.3.3.18
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase (EC 5.3.3.18, paaG (gene), 1,2-epoxyphenylacetyl-CoA isomerase) is an enzyme with systematic name 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase.[1][2] This enzyme catalyses the following chemical reaction

2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA 2-oxepin-2(3H)-ylideneacetyl-CoA

The enzyme catalyses the reversible isomerization of 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA.

References

  1. Ismail, W.; El-Said Mohamed, M.; Wanner, B.L.; Datsenko, K.A.; Eisenreich, W.; Rohdich, F.; Bacher, A.; Fuchs, G. (2003). "Functional genomics by NMR spectroscopy. Phenylacetate catabolism in Escherichia coli". Eur. J. Biochem. 270 (14): 3047–3054. doi:10.1046/j.1432-1033.2003.03683.x. PMID 12846838.
  2. Teufel, R.; Mascaraque, V.; Ismail, W.; Voss, M.; Perera, J.; Eisenreich, W.; Haehnel, W.; Fuchs, G. (2010). "Bacterial phenylalanine and phenylacetate catabolic pathway revealed". Proc. Natl. Acad. Sci. USA. 107 (32): 14390–14395. doi:10.1073/pnas.1005399107. PMC 2922514Freely accessible. PMID 20660314.

External links

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