2,2'-Dipyridyldisulfide
Names | |
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Preferred IUPAC name
2,2'-Disulfanediyldipyridine | |
Other names
1,2-Di(pyridin-2-yl)disulfane (not recommended) 2,2'-Dipyridyldisulfide 2,2'-Dipyridyldisulphide Aldrithiol-2 | |
Identifiers | |
2127-03-9 | |
3D model (Jmol) | Interactive image Interactive image |
ChEMBL | ChEMBL118678 |
ChemSpider | 58603 |
ECHA InfoCard | 100.016.676 |
UNII | L6X912UPBU |
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Properties | |
C10H8N2S2 | |
Molar mass | 220.31 g·mol−1 |
Melting point | 56 to 58 °C (133 to 136 °F; 329 to 331 K) |
Hazards | |
Main hazards | Irritant (Xi) |
R-phrases | R36/37/38 |
S-phrases | S36/37/39 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
verify (what is ?) | |
Infobox references | |
2,2'-Dipyridyldisulfide, sometimes known as DPS, is used for preparing thiols[1][2] and activating or protecting carboxylic acid with triphenylphosphine in the following reaction.[3]
Uses
It is also used in molecular biology as an oxidising agent, for example to oxidise free thiols to form disulfide bonds in proteins.
References
- ↑ Futaki S. and Kitagawa K. (1994). "Peptide-Unit Assembling Using Disulfide Cross-Linking - a New Approach for Construction of Protein Models". Tetrahedron Lett. 35 (8): 1267–1270. doi:10.1016/0040-4039(94)88040-9.
- ↑ "Special Reagents for Thiol Groups". Aldrichimica Acta. 4 (3): 33–46.
- ↑ Thalmann A., Oertle K. and Gerlach H. "Synthesis of ricinelaidic acid lactone". Org. Synth. 7: 470.
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