19-Iodocholesterol

19-Iodocholesterol

Names
IUPAC name (3S,8S,9S,10S,13R,14S,17R)-10-(iodomethyl)-13-methyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
Identifiers
CAS Number	37414-03-2 N
3D model (Jmol)	Interactive image
ChemSpider	20086815 Y
ECHA InfoCard	100.048.618
PubChem	21150757
InChI InChI=1S/C27H45IO/c1-18(2)6-5-7-19(3)23-10-11-24-22-9-8-20-16-21(29)12-15-27(20,17-28)25(22)13-14-26(23,24)4/h8,18-19,21-25,29H,5-7,9-17H2,1-4H3/t19-,21+,22+,23-,24+,25+,26-,27-/m1/s1 Y Key: FIOAEFCJGZJUPW-FTLVODPJSA-N Y InChI=1/C27H45IO/c1-18(2)6-5-7-19(3)23-10-11-24-22-9-8-20-16-21(29)12-15-27(20,17-28)25(22)13-14-26(23,24)4/h8,18-19,21-25,29H,5-7,9-17H2,1-4H3/t19-,21+,22+,23-,24+,25+,26-,27-/m1/s1 Key: FIOAEFCJGZJUPW-FTLVODPJBR
SMILES CC(C)CCC[C@@H](C)[C@H]3CC[C@H]2[C@@H]4C\C=C1\C[C@@H](O)CC[C@]1(CI)[C@H]4CC[C@@]23C
Properties
Chemical formula	C27H45IO
Molar mass	512.56 g·mol−1
Pharmacology
ATC code	V09XA02 (WHO) (131I)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

19-Iodocholesterol is a derivative of cholesterol with an iodine atom in the 19-position. When the iodine atom is a radioactive isotope (iodine-125 or iodine-131), it is used as an adrenal cortex radiocontrast agent for in the assessment of patients suspected of having Cushing's syndrome, hyperaldosteronism, pheochromocytoma and adrenal remnants following total adrenalectomy.^[1]

References